黄颖钰  

南京大学医学院 副教授 博士生导师

2024年度国家级青年人才(海外)

 

电话:

邮箱:yingyu_huang@hotmail.com

地址:南京市汉口路22号东南楼南京大学医学院

 
  个人简介:

工作经历:
2025.01 至今 南京大学医学院 准聘副教授
2022.04 – 2024.12 德克萨斯达拉斯分校/西南医学中心 研究科学家
2020.08 – 2022.04 德克萨斯大学达拉斯分校博士后研究员

教育背景:
2015.08 – 2020.08 德克萨斯大学达拉斯分校 化学博士
2011.08 – 2015.07 北京理工大学 化学学士

科研方向:
1) 纳米材料活体清除途径
2) 纳米生物相互作用
3) 肾脏纳米药物

 
     
     
  代表性论文:

1. Huang, Y.; Zheng, J.; Yu, M., Nanoparticle Transport in Proximal Tubules with Rhabdomyolysis-Induced Necrosis. Angew. Chem. Int. Ed. e202417024. (2024)

2. Huang, Y.; Yu, M.; Zheng, J., Charge barriers in the kidney elimination of engineered nanoparticles. PNAS 121, 23, e2403131121. (2024)

3. Huang, Y.; Ning, X.; Ahrari, S.; Cai, Q.; Rajora, N.; Saxena, R.; Yu,M.; Zheng, J., Physiological principles underlying the kidney targeting of renal nanomedicines. Nature Reviews Nephrology 20, 354-370. (2024)

4. Huang, Y.; Xiao, W.; Ahrari, S.; Yu,M.; Zheng, J., Crosstalk between hepatic glutathione efflux and tumor targeting of ICG-conjugated gold nanoparticles. Angew. Chem. Int. Ed. 62, e202308909 (2023)

5. Huang, Y.; Yu, M.; Zheng, J., Proximal tubules eliminate endocytosed gold nanoparticles through an organelle-extrusion-mediated self-renewal mechanism. Nature Nanotechnology 18, 637–646. (2023)

6. Jiang, X.; Zhou, Q.; Du, B.; Li, S.; Huang, Y.; Chi, Z.;Yu, M.; Zheng, J., Noninvasive Monitoring of Hepatic Glutathione Depletion through Fluorescence Imaging and Blood Test. Science Advances 7, eabd9847. (2021)

7. Tang, S.1; Huang, Y.1; Zheng, J., Salivary Excretion of Renal‐Clearable Silver Nanoparticles. Angewandte Chemie, 132, 20066-20070. (2020) Both authors contributed equally.

8. Peng, C.1; Huang, Y.1; Zheng, J., Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance. Journal of Controlled Release, 322, 64-80. (2020) Both authors contributed equally.

9. Jiang, X.; Du, B.; Huang, Y.; Yu, M.; Zheng, J., Cancer Photothermal Therapy with ICG-Conjugated Gold Nanoclusters. Bioconjugate Chemistry, 31 (5), 1522-1528. (2020)

10. Du, B.; Jiang, X.; Huang, Y.; Li, S.; Lin, J. C.; Yu, M.; Zheng, J., Tailoring Kidney Transport of Organic Dyes with Low-Molecular-Weight PEGylation. Bioconjugate Chemistry, 31 (2), 241-247. (2020)

11. Zhang, B.; Huang, Y.; Vinluan, R.; Wang, S.; Cui, C.; Lu, X.; Peng, C.; Zhang, M.; Zheng, J.; Gao, P.-X., Enhancing ZnO nanowire gas sensors using Au/Fe2O3 hybrid nanoparticle decoration. Nanotechnology, 31 (32), 325505. (2020)

12. Peng, C.; Xu, J.; Yu, M.; Ning, X.; Huang, Y.; Du, B.; Hernandez, E.; Kapur, P.; Hsieh, J.-T.; Zheng, J., Tuning the In Vivo Transport of Anticancer Drugs Using Renal-Clearable Gold Nanoparticles. Angewandte Chemie, 131 (25), 8567-8571. (2019)

13. Huang, Y.; Fuksman, L.; Zheng, J., Luminescence mechanisms of ultrasmall gold nanoparticles. Dalton Transactions, 47 (18), 6267-6273. (2018)

14. Sun, S.; Huang, Y.; Zhou, C.; Chen, S.; Yu, M.; Liu, J.; Zheng, J., Effect of Hydrophobicity on Nano-Bio Interactions of Zwitterionic Luminescent Gold Nanoparticles at the Cellular Level. Bioconjugate chemistry, 29 (6), 1841-1846. (2018)

15. Jiang, X.; Du, B.; Huang, Y.; Zheng, J., Ultrasmall noble metal nanoparticles: Breakthroughs and biomedical implications. Nano today, 21, 106-125. (2018)